Insalubrious, a.
Etymology: [Pref. in- not + salubrious: cf. L. insalubris, F. insalubre.]
Not salubrious or healthful; unwholesome; as, an insalubrious air or climate.
Shades of meaning
Fernald has no entry of its own for insalubrious; he lists it under pernicious.
He lists it without comment; the entries above explain its neighbors.