Detrimental, a.
Causing detriment; injurious; hurtful. Neither dangerous nor detrimental to the donor. Addison.
Syn. -- Injurious; hurtful; prejudicial; disadvantageous; mischievous; pernicious.
Shades of meaning
Fernald has no entry of its own for detrimental; he lists it under pernicious.
He lists it without comment; the entries above explain its neighbors.