Hurtful, a.
Tending to impair or damage; injurious; mischievous; occasioning loss or injury; as, hurtful words or conduct.
Syn. -- Pernicious; harmful; baneful; prejudicial; detrimental; disadvantageous; mischievous; injurious; noxious; unwholesome; destructive. -- Hurt"ful*ly, adv. -- Hurt"ful*ness, n.
Shades of meaning
Fernald has no entry of its own for hurtful; he lists it under pernicious.
He lists it without comment; the entries above explain its neighbors.