DIsease, n.
Etymology: [OE. disese, OF. desaise; des- (L. dis-) + aise ease. See Ease.]
1. Lack of ease; uneasiness; trouble; vexation; disquiet. [Obs.] So all that night they passed in great disease. Spenser. To shield thee from diseases of the world. Shak.
2. An alteration in the state of the body or of some of its organs, interrupting or disturbing the performance of the vital functions, and causing or threatening pain and weakness; malady; affection; illness; sickness; disorder; -- applied figuratively to the mind, to the moral character and habits, to institutions, the state, etc. Diseases desperate grown, By desperate appliances are relieved. Shak. The instability, injustice, and confusion introduced into the public counsels have, in truth, been the mortal diseases under which popular governments have every where perished. Madison. Disease germ. See under Germ.
Syn. -- Distemper; ailing; ailment; malady; disorder; sickness; illness; complaint; indisposition; affection. -- Disease, Disorder, Distemper, Malady, Affection. Disease is the leading medical term. Disorder meanirregularity of the system. Distemper is now used by physicians only of the diseases of animals. Malady is not a medical term, and is less used than formerly in literature. Affection has special reference to the part, organ, or function disturbed; as, his disease is an affection of the lungs. A disease is usually deep-seated and permanent, or at least prolonged; a disorder is often slight, partial, and temporary; malady has less of a technical sense than the other terms, and refers more especially to the suffering endured. In a figurative sense we speak of a disease mind, of disordered faculties, and of mental maladies.
1 other Webster entry under this spelling
Disease, v. t. [imp. & p. p. Diseased; p. pr. & vb. n. Diseasing.]
1. To deprive of ease; to disquiet; to trouble; to distress. [Obs.] His double burden did him sore disease. Spenser.
2. To derange the vital functions of; to afflict with disease or sickness; to disorder; -- used almost exclusively in the participle diseased. He was diseased in body and mind. Macaulay.
Shades of meaning
Disease is the general term for any deviation from health; in a more limited sense it denotes some definite morbid condition; disorder and affection are rather partial and limited; as, a nervous affection; a disorder of the digestive system. Sickness was generally used in English speech and literature, till the close of the eighteenth century at least, for every form of physical disorder, as abundantly appears in the English Bible: "Jesus went about ... healing all manner of sickness and all manner of disease among the people," Matt. iv, 23; "Elisha was fallen sick of his sickness whereof he died," 2 Kings xiii, 14. There is now, in England, a tendency to restrict the words sick and sickness to nausea, or "sickness at the stomach," and to hold ill and illness as the only proper words to use in a general sense. This distinction has received but a very limited acceptance in the United States, where sick and sickness have the earlier and wider usage. We speak of trifling ailments, a slight indisposition, a serious or a deadly disease; a slight or severe illness; a painful sickness. Complaint is a popular term, which may be applied to any degree of ill health, slight or severe. Infirmity denotes a chronic or lingering weakness or disability, as blindness or lameness.