Disquiet, n.
Want of quiet; want of tranquility in body or mind; uneasiness; restlessness; disturbance; anxiety. Swift.
2 other Webster entries under this spelling
Disquiet, a.
Deprived of quiet; impatient; restless; uneasy. [R.] Shak.
Disquiet, v. t. [imp. & p. p. Disquieted; p. pr. & vb. n. Disquieting.]
To render unquiet; to deprive of peace, rest, or tranquility; to make uneasy or restless; to disturb. Why art thou cast down, O my soul, and why art thou disquieted within me Ps. xlii. 11. As quiet as these disquieted times will permit. Sir W. Scott.
Syn. -- To harass; disturb; vex; fret; excite; agitate.
Shades of meaning
Fernald has no entry of its own for disquiet; he lists it under anxiety.
Where he writes about it:
Anxiety is, according to its derivation, a choking disquiet, akin to anguish; anxiety is mental; anguish may be mental or physical; anguish is in regard to the known, anxiety in regard to the unknown; anguish is because of what has happened, anxiety because of what may happen. — from anxiety
Fretting or fretfulness is a weak complaining without thought of accomplishing or changing anything, but merely as a relief to one's own disquiet. — from anxiety